Iconoclast: A Neuroscientist Reveals How to Think Differently

  • Before the monkeys learned the association between litha nd jice, the dopmaine neurson fired in resposne to the jice itself… after a period of training, hwoever, the monkeys learned to associate the lgiht wit hthe juice, and the domaine neurons stopped firing ot the juice and began firing to the light (1) – page 45 2
  • Most people avoid the urn with the unknown probabilities regardless of what the other urn contains… two regions were more strongly activated in response to ambiguity… the orbitofrontal cortex and the amygdala (2) – pages 75-76 3
  • When people reappraised emotional scenecs, meanign they replaces a negative reacton with a positive one, activity in the left prefonrtla cortex increased, in an amount hta tcorrealtedw ith the decrease in the amygdala (3) – page 79 3
  • Greater activity in the dopamine rich areas of the brain when winning was more liekly… how much greater depended on the partiucalr combination of gens the indivudla had… people with the Val/Val form of COMT and the 10r form of the DAT showed no relationship bweteen brain activity and winning… thse people were insentivie to the level of risk… these people also socred high in sensation seeking… these particualr variants are associatedw ieth lower dopamine activity (4) – pages 127-128 5
  • Participants with amygdala damage judged ther people to be more trustworthy (5) – page 139 6
  • Participants displayed more amygdala activation to Afircan American faces than Caucian ones.. the level of amygdala activation correlated with two subconscious measures of racial bias (6) – page 140 6
  • Birds had learned the trick of opening milk bottles from each other (7) – page 183 8
  • Individuals who scored high on the personality traits of novelty seeking and thirll eeking had the hgihest level of striatal activation (8) – pages 192-193 8
  • Parts of the striatum became activie when subjects viewed appetizing or disgusting foods… the degree of straitl activationw as linked to peraonlity traits…  subjects who scored on “Behavioral Approach” ad higher activation in response to appetizing foods.. the relationship did not exist for disgusting oods (9) – pages 192-193 8
  • The level of COMT activity doubled in the adult brain comapred to the infant brain (10) – page 199 8
  • When women were administered testosterone, they didn’t subconsciously mimic facial expressions…  It also decreased startle response (11) – page 220 Appe
  • Oxytocin increased ability to read facial expressions (12) – page 221 Appe
  • Amygdala actvation in response to fear-inducing picture was decreased by oxytocin adminstration (13) – page 221 Appe

References

  1. Neural activity in monke ventral striatum related to the expectaon of reward
  2. Risk ambiguity and savage axioms
  3. Rethinking feelings an fmri study of hte cognitive regu;atopn of emoton, Contributions of the amygdala
  4. Gene gene interaction associatedw ith neural reward sensitivity
  5. The human amygdala in social judgment
  6. PErformance on indeirect measures of race evaluatin rpedics amygdala activatn, The role of social gorups in the pesristence of learned fear, An fmri investigaiton of race related amygdala activity in african american and caucaisn american individauls
  7. The opening of milk bottles by birds, Furhter observations on the opening of milk bottles by birds
  8. Predition error as a lienra ufniton of reward proabiltiy is coded in huamn nucleus accumebns
  9. Individual differences in reward drive predict neural respones to images of food
  10. Cateho methyltranserane eznyme activity and protein expresison in human prefrontal cortex across the postnatl lifespan
  11. Testosterone adminstriation reduces empathetic behavior a facial micity, A singel admisntration of testoerene reduces fear potentiated startle in humans
  12. Oxytocin imroves mind reading in huamns
  13. oxytocin modulates neural circuity ofr social cognition and fear in humans